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Description

Thus, exclusive glycolytic metabolism of the 60 nmol/mg glucosyl residues mobilized from glycogen to lactate [128] during 20 min starvation would regenerate 180 nmol/mg ATP, thereby having then potential to fuel 6 times a complete regeneration of the specific cellular ATP pool (around 30 nmol/mg) of cultured astrocytes and to supply the basal ATP consumption (4 nmol/(min x mg)) for 45 min

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Indeed, vincristine and verapamil both were shown to decrease the photolabeling of MRP1 by [ 125 I] LY475776, an inhibitor of LTC 4 transport 53

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Both macroglia (astrocytes and Mller cells) and microglia, as well as infiltrating monocytes, are involved in the neuroinflammatory process and in the immune-mediated neurodegenerative process of RGCs that occurs in glaucoma, producing proinflammatory cytokines and complement components (Nickells et al., 2012

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